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. 1967 Sep;15(5):1240–1243. doi: 10.1128/am.15.5.1240-1243.1967

Treatment of Mengovirus Infection in Mice with Statolon

Frank F Pindak 1, Jerome P Schmidt 1
PMCID: PMC547173  PMID: 4294823

Abstract

A single intraperitoneal injection of statolon was shown to exert a therapeutic effect on mice previously injected with the large plaque-forming variant of mengovirus. The ld50 and survival time data demonstrated that such treatment was effective when given 2 to 48 hr after infection. No protective effect was apparent when statolon was administered 3, 4, or 5 days after the viral challenge. It was concluded that statolon, or other similar interferon inducers, may be of therapeutic value in instances of accidental or other known exposure to hazardous viral agents.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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