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. 1967 Nov;15(6):1316–1323. doi: 10.1128/am.15.6.1316-1323.1967

Characteristics of Clostridium botulinum Type F Isolated from the Pacific Coast of the United States

M W Eklund 1, F T Poysky 1, D I Wieler 1
PMCID: PMC547191  PMID: 4865980

Abstract

Some of the physiological and biochemical characteristics of a type F strain recently isolated from the United States were studied and compared with those of the prototype Langeland type F strain. The recent isolates were nonproteolytic, fermented sucrose and ribose, produced spores of low thermal resistance, produced a protoxin activated by trypsin, and grew and produced toxin at 38 F (3.3 C) from a spore inoculum. The prototype Langeland strain was proteolytic, did not ferment sucrose or ribose, and produced spores of relatively high thermal resistance, and the toxin of 3-day-old cultures was not activated by trypsin. Approximately two to three times the minimal lethal dose (MLD) of type F toxin from either Langeland or nonproteolytic strains was cross-neutralized by 1,000 anti-MLD of type E antitoxin. Antitoxin serums prepared by immunizing rabbits with the toxoid of the nonproteolytic type F isolate neutralized the toxin of the Langeland strain, but did not show cross-neutralization with the toxins of other types of Clostridium botulinum.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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