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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Genesis. 2017 Apr 18;55(6):10.1002/dvg.23034. doi: 10.1002/dvg.23034

Fig. 11.

Fig. 11

Distribution of Cre and RFP signals in Wnt1-Cre/R26-RFP embryos. A: Bright-field (top panel) and fluorescent (bottom panel) images of whole Wnt1-Cre/R26-RFP embryos at 5–7 somite stages. In contrast to the P0-Cre/R26-RFP embryos, RFP signals were detected in midbrain (mb) region (arrowheads), but not obvious in the hindbrain (hb, arrows). B and C: Single-plane laser scanning confocal photomicrographs of a transverse section of a 6-somite Wnt1-Cre(+)/R26-RFP(+) embryo at the midbrain (B) and hindbrain (C) level. Arrows point to the trigeminal NC region that was devoid of RFP and Cre signals. Scale bars: 250 μm in A; 50 μm in B and C.