Table 5. Rate ratios (RR) and 95% confidence intervals (CI) for chronic conditions by demographic and treatment-related factors among survivors of Ewing sarcoma.

Any grade 1-5 condition	RR (95% CI)
Radiation Exposure
Yes	2.1 (1.0-4.4)
No	1.0
Surgery Exposure
Yes	1.0 (0.6-1.7)
No	1.0
Two or more grade 1-5 conditions
Radiation Exposure
Yes	0.8 (0.3-1.9)
No	1.0
Surgery Exposure
Yes	1.0 (0.5-2.0)
No	1.0
Cardiac condition	RR (95% CI)
Anthracycline Dose
None	1.0
<300 mg/m2	1.0 (0.4-2.6)
≥300 mg/m2	1.0 (0.5-2.1)
Chest Radiation
No	1.0
Yes	1.9 (1.0-3.5)
Pulmonary condition
Chest Radiation
Yes	1.2 (0.6-2.4)
No	1.0
Musculoskeletal complication
Radiation
Yes	6.8 (1.6-29.1)
No	1.0
Surgery
Yes	1.0 (0.5-1.9)
No	1.0
Neurological condition
Surgery
Yes	0.8 (0.4-1.7)
No	1.0

^*The results for each outcome are from regression analysis adjusting for age (using natural cubic splines), smoking, and BMI as time-dependent variables, sex, race, year of diagnosis, and age at diagnosis.