Fig. 6.

Loss of viral control leads to increased levels of IP-10, IFN-y and MIP1-α in the serum. Serum from five healthy donors (HD), eight chronic progressors (CP), eight elite suppressors (ES), and two acute progressors (AP) were tested. Chronic progressor 1 (VP1) was tested at one time point. Acute controller 1 (AC1) was tested at four time points, two prior to loss of viremic control (AC1c: D50, D160) and two post loss of viremic control (AC1v: D280, D335). All samples were tested using the MSD multiplex and reported as pg/ml, the lower limit of quantification (LLOQ) is indicated as a dotted line for each analyte.