Abstract
A new basic, water-soluble antibiotic designated LL-AC541, produced by a strain of Streptomyces hygroscopicus (NRRL 3111), was isolated as a hydrochloride salt; [α]D25, — 58°, melting point, 200 to 215 C (decomposition). It is structurally related to streptothricin but does not contain β-lysine. Isolation procedures, physicochemical properties, antimicrobial spectrum, and in vivo testing results are presented. Another very closely related antibiotic obtained from the same fermentation is briefly described.
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Selected References
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