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. 1968 Aug;16(8):1245–1250. doi: 10.1128/am.16.8.1245-1250.1968

Production of Highly Labeled Adenoviruses

J Paul Burnett 1, A O Summers 1,1, J A Harrington 1, A C Dwyer 1
PMCID: PMC547627  PMID: 5675512

Abstract

A method is described for increasing the incorporation of radioactive thymidine into adenovirus deoxyribonucleic acid by the use of amethopterin. In addition, a modified procedure is presented for the preparation of highly purified adenoviruses. This procedure, which employs enzymatic digestion of cellular debris, obviates the necessity for fluorocarbon treatment of crude virus suspensions, and routinely provides excellent recovery of virus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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