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. 1968 Dec;16(12):1822–1825. doi: 10.1128/am.16.12.1822-1825.1968

Production of Streptococcal M-Typing Antisera

I. Antigenic Response in Different Breeds of Rabbits

Richard R Facklam 1, Max D Moody 1
PMCID: PMC547778  PMID: 5726157

Abstract

M-antigens of seven M-types of group A streptococci were used to compare antigenic response in six breeds of rabbits: New Zealand White, New Zealand Red, Dutch, Googy, California, and Palomino. No appreciable differences among breeds were demonstrated. M-types used for immunization varied considerably in their ability to evoke a response of an antibody which met rigid criteria for streptococcal M-typing antisera. The importance of the injection and bleeding schedule and absorption conditions for preparing type-specific absorbed antisera were demonstrated. Evaluating and processing sera from individual animals at an optimal time rather than using pooled sera enhanced the possibilities for preparing satisfactory type-specific antisera.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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