Patients in the +DSA/high+XM group had lower GFR at 1,2 and 5 years posttransplant than the −DSA/-XM group as measured by iothalamate clearance, p<0.01. GFR was between the −DSA/-XM and +DSA/-XM, +DSA/low+XM, and −DSA/+XM groups at 1,2 and 5 years. Proteinuria was also higher in the +DSA/high+XM group as compared to the −DSA/-XM group at 1 year posttransplant, p<0.01.