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. 2016 Jun 25;8(22):35656–35668. doi: 10.18632/oncotarget.10290

Table 1. Clinicopathological characteristics of patient tumors (n = 65).

Stage III IBC mIBC P- value
N % N %
All 21 100.0 44 100.0 NA
CTC per 7.5 mL of blood
 ≥ 1 7 33.3 33 75.0 0.002
 ≥ 5 1 4.8 22 50.0 0.001
Grade
 1 and 2 9 42.9 14 31.8 0.58
 3 12 57.1 29 65.9
 unknown 0 0.0 1 2.3
Histology
 Invasive ductal carcinoma 18 85.7 36 81.8 0.74
 Other 3 14.3 8 18.2
ER/PR status
 Negative for both 6 28.6 24 54.5 0.07
 Positive for either 15 71.4 20 45.5
HER2 status
 Amplified 10 47.6 14 31.8 0.78
 Normal 11 52.4 30 68.2
ER/PR and HER2/neu status
 Triple receptor negative 5 23.8 17 38.6 0.28
 Non-triple receptor negative 16 76.2 27 61.4
Sites of metastases
 Non-visceral NA NA 27 61.4 NA
 Visceral NA NA 17 38.6
Bone metastases
 Present NA NA 23 52.3 NA
 Absent NA NA 21 47.7
No. of metastasis
 1 NA NA 21 47.7 NA
 ≥2 NA NA 23 52.3
Treatment
 Treatment naïve 21 100.0 14 31.8 NA
 Pretreated 0 0.0 30 68.2

Abbreviations: NA, not applicable; ER, estrogen receptor; PR, progesterone receptor.