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EMBO Reports logoLink to EMBO Reports
. 2017 Jul 3;18(7):1264. doi: 10.15252/embr.201744508

Structural basis for recruitment of BRCA2 by PALB2

Antony W Oliver, Sally Swift, Christopher J Lord, Alan Ashworth, Laurence H Pearl
PMCID: PMC5494498  PMID: 28673926

Abstract

graphic file with name EMBR-18-1264-g001.jpg


We note that the amino acid sequence of BRCA2(21–39) peptides sometimes contains an inadvertent typographical error, where amino acids 23 and 24 have been inverted. Please see the following:

  1. Methods, “Peptide binding and competition assays”, page 995

  2. Supplementary information, “Peptide Binding/Competition Assays”, pages 4 and 5

  3. Supplementary information, “Fluorescence Polarisation”, page 5

The correct peptide amino acid sequences are as follows:

  • BRCA2(21–39, WT): biotin‐GG‐KADLGPISLNWFEELSSEA

  • BRCA2(21–39, W31C): biotin‐GG‐KADLGPISLNCFEELSSEA

  • BRCA2(21–39, non‐biotinylated): KADLGPISLNWFEELSSEA

  • BRCA2(21–39, fluorescein): fluorescein‐GG‐KADLGPISLNWFEELSSEA


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