Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jul 4;4(3):ENEURO.0142-17.2017. doi: 10.1523/ENEURO.0142-17.2017

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Gonsalvez et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Figure 2. — Cyclo-dPAKKR ameliorates EAN in a dose-dependent manner. Time course of disease severity in rats subjected to EAN following daily administration of either vehicle control or Cyclo-dPAKKR from day 1 (data: mean ± SEM, n = 6–7/group, Mann–Whitney U test). A, Cyclo-dPAKKR reduced disease severity in rat EAN in a dose-dependent manner (3 mg/kg group: *p < 0.01, 10 mg/kg group: **p < 0.001). B, EAN rats treated with cyclo-dPAKKR beyond the disease peak (day 17) exhibited a significantly faster recovery compared with vehicle controls (*p < 0.001).