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. Author manuscript; available in PMC: 2017 Jul 4.
Published in final edited form as: Radiographics. 2015 Nov 20;36(1):162–175. doi: 10.1148/rg.2016150030

Table 2.

Benign Conditions That Mimic Prostate Carcinoma at MR Imaging

Conditions Histologic and Anatomic Features
Anatomic
 Anterior fibromuscular stroma Dense fibromuscular band anterior to the transition zone
 Surgical capsule Band of fibromuscular and compressed glandular tissue between the transition zone and peripheral zone
 Central zone Complex crowded glands and dense stroma surrounding the ejaculatory ducts
 Periprostatic vein Venous plexus closely associated with the pseudocapsule
 Periprostatic lymph nodes Lymph nodes adjacent to the lateral or posterolateral prostate

Benign pathologic
 Stroma-rich BPH Stromal fibromuscular proliferation in the transition zone and occasionally in the peripheral zone
 Bacterial prostatitis (acute or chronic) Inflammatory (neutrophils or lymphocytes) infiltrate with or without glandular atrophy
 Mycobacterial granulomatous prostatitis Granulomatous inflammation with or without central caseation
 Malacoplakia Granulomatous inflammation with Michaelis-Gutmann bodies
 Atrophy Crowded glands with scant cytoplasm and nuclear crowding
 Necrosis Coagulative necrosis with surrounding chronic inflammatory infiltrate and atrophy
 Calcification Concreted prostatic secretions or calcified corpora amylacea
 Hemorrhage Hemorrhage