Table 4.
Risk of mortality associated with benzodiazepine initiation versus selective serotonin reuptake inhibitors (SSRIs) initiation in unadjusted, propensity score and high dimensional propensity score matched analyses
| Analysis | Benzodiazepine initiators | SSRI initiators | Hazard ratio (95% CI) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No of patients | No of Events | Person years | Incidence/1000 person years | No of patients | No of events | Person years | Incidence/1000 person years | |||
| Unadjusted | 1 063 845 | 6008 | 465 228 | 12.9 | 649 400 | 2276 | 282 646 | 8.1 | 1.61 (1.53 to 1.68) | |
| 1:1 propensity score matched | 563 088 | 2076 | 245 380 | 8.5 | 563 088 | 2096 | 245 252 | 8.5 | 0.99 (0.93 to 1.05) | |
| 1:1 high dimensional propensity score matched | 549 022 | 2213 | 239 380 | 9.2 | 549 022 | 2032 | 239 261 | 8.5 | 1.09 (1.03 to 1.16) | |