The images for Figs 2 and 3 are incorrectly switched. The image that appears as Fig 2 should be Fig 3 and the image that appears as Fig 3 should be Fig 2. The figure captions appear in the correct order.
Fig 2. Examples of two chemicals (digitonin vs. mitomycin C) with different kinetics of cytotoxicity.
Blue: HEK293; red: HepG2. Filled circle (glo); hollow circle (flor); the arrow represents the earliest time interval where the maximum cytotoxic effect was obtained (filled arrow head: glo; hollow arrow head: flor).
Fig 3. Comparison of number of actives in four assays.
The number of actives detected in the four assays at the six different time points. Blue: HEK293 cell line; red: HepG2 cell line. Filled circle: glo assay technology; hollow circle: flor assay technology.
Reference
- 1.Hsieh J-H, Huang R, Lin J-A, Sedykh A, Zhao J, Tice RR, et al. (2017) Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage. PLoS ONE 12(5): e0177902 https://doi.org/10.1371/journal.pone.0177902 [DOI] [PMC free article] [PubMed] [Google Scholar]


