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Confocal fluorescence microscopic images of the BxPC-3 cells incubated with carboxyfluorescein-encapsulated polymersomes under normoxic (A) and hypoxic (B) conditions for 1, 2, and 3 h. (C) Quantitative fluorescence integral density for the images shown in panels A and B indicating uptake in cells cultured under normoxic (black) and hypoxic (red) conditions (N = 3, *p < 0.05).
