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Biosynthesis of sialoglycoconjugates in vertebrates. Enzymes are italicised: UDP‐GlcNAc 2‐epimerase/ManNAc kinase (GNE), CMP‐sialic acid synthetase (CMAS), CMP‐sialic acid transporter (SLC35A1). Cell organelles are shaded in grey. CMP‐Neu5Ac is a feedback inhibitor of GNE (−).
