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A. TKO mice were treated daily with vehicle or BEZ235 beginning at post-natal days 2 through 6, 22 through 26, 42 through 46, and intraocular pressure (IOP) was measured until an endpoint measurement of 20 mmHg was reached. B. Kaplan-Meier analysis of vehicle and BEZ235 treated retinoblastoma bearing mice.
