Table 3. False-positive report probability values for associations between the TERT rs2736100 T>G polymorphism and overall cancer risk.
Genetic models | OR (95% CI) | P | Power | Prior Probability | |||||
---|---|---|---|---|---|---|---|---|---|
0.25 | 0.1 | 0.01 | 0.001 | 0.0001 | 0.00001 | ||||
Homozygous (GG vs. TT) | 1.39 (1.26-1.54) | <0.001 | 0.555 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
Heterozygous (TG vs. TT) | 1.16 (1.11-1.23) | <0.001 | 0.872 | 0.000 | 0.000 | 0.000 | 0.001 | 0.008 | 0.073 |
Recessive (GG vs. TG + TT) | 1.25 (1.16-1.35) | <0.001 | 0.841 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.002 |
Dominant (TG +GG vs. TT) | 1.23 (1.15-1.31) | <0.001 | 0.957 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
Allele (G vs. T) | 1.17 (1.12-1.23) | <0.001 | 0.839 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |