. 2017 Mar 15;8(24):39818–39832. doi: 10.18632/oncotarget.16242

Table 3. Summary of OR and 95% CI for association of rs144848 polymorphism with cancer risk by cancer type stratification.

Subgroup	p for heterogeneity	I² (%)	OR (95% CI)	p value	Effects model
N allele vs H allele
Breast cancer	0.679	0.0	1.028 (0.997-1.060)	0.075	fixed
Ovarian cancer	0.359	9.1	1.024 (0.981-1.068)	0.280	fixed
NHL	0.518	0.0	1.110 (1.023-1.205)	0.012^a	fixed
Others	0.658	0.0	1.158 (1.074-1.249)	<0.001^a	fixed
NH vs NN
Breast cancer	0.890	0.0	1.029 (0.988-1.072)	0.166	fixed
Ovarian cancer	0.080	46.8	1.015 (0.959-1.074)	0.604	fixed
NHL	0.954	0.0	1.090 (0.977-1.215)	0.122	fixed
Others	0.090	47.5	1.117 (1.009-1.236)	0.033^a	fixed
HH vs NN
Breast cancer	0.491	0.0	1.056 (0.978-1.139)	0.162	fixed
Ovarian cancer	0.446	0.0	1.063 (0.957-1.180)	0.253	fixed
NHL	0.294	19.0	1.263 (1.035-1.542)	0.022^a	fixed
Others	0.653	0.0	1.439 (1.199-1.726)	<0.001^a	fixed
Dominant model
Breast cancer	0.852	0.0	1.033 (0.994-1.074)	0.097	fixed
Ovarian cancer	0.156	35.7	1.022 (0.969-1.079)	0.420	fixed
NHL	0.855	0.0	1.118 (1.008-1.240)	0.035^a	fixed
Others	0.237	26.3	1.162 (1.055-1.280)	0.002^a	fixed
Recessive model
Breast cancer	0.477	0.0	1.044 (0.969-1.124)	0.259	fixed
Ovarian cancer	0.351	10.3	1.057 (0.954-1.170)	0.290	fixed
NHL	0.277	21.6	1.216 (1.002-1.476)	0.048^a	fixed
Others	0.377	6.2	1.346 (1.130-1.603)	0.001^a	fixed

^a Statistically significant