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. 2017 Jul 12;5:74. doi: 10.1186/s40168-017-0291-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Effect of intramammary infection with E. coli and subsequent treatment with ceftiofur hydrochloride (48, 72, 96, 120, and 144 h) on relative abundance of the 25 most prevalent families in unchallenged untreated quarters (a, N = 11), in unchallenged ceftiofur-infused quarters (b, N = 5), in challenged untreated quarters (c, N = 3), and in challenged and ceftiofur-treated quarters (d, N = 5). Black diamonds represent experimental infection with 100 CFU of E. coli, and grey circles represent intramammary treatment with ceftiofur