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. 1979 Jan;23(1):1–7. doi: 10.1128/iai.23.1.1-7.1979

Immunoglobulin-binding structure on bovine group G streptococci different from type III Fc receptors on human group G streptococci.

E B Myhre, O Holmberg, G Kronvall
PMCID: PMC550679  PMID: 570553

Abstract

The immunoglobulin G (IgG)-binding capacity of 54 group G streptococci of human and bovine origin was investigated. Of 20 human strains, 17 carried a surface component which could combine with human IgG and bovine IgG1 and IgG2. Inhibition experiments with unlabeled human IgG and with a panel of animal sera revealed that the same surface component was involved in the binding of human as well as bovine immunoglobulins. Of 16 beta-hemolytic bovine group G streptococci, 13 reacted with human IgG but not with bovine IgG1 or IgG2. This binding structure was different from the type III Fc reactivity found in human group G streptococci. All human strains, including the three IgG Fc-nonreactive strains, fermented trehalose, in contrast to all bovine beta-hemolytic strains, which were negative. Immunoglobulin Fc reactivity is thus a feature not only of human strains but also of some bovine strains.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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