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. 1980 Jan;27(1):264–267. doi: 10.1128/iai.27.1.264-267.1980

Rate of clearance of virulent Treponema pallidum (Nichols) from the blood stream of normal, Mycobacterium bovis BCG-treated, and immune syphilitic rabbits.

S Graves
PMCID: PMC550754  PMID: 6987173

Abstract

The rate of clearance of virulent Treponema pallidum (Nichols) from the blood stream of normal rabbits and rabbits previously treated with Mycobacterium bovis BCG was similar, there being treponemes still circulating 8 h after intravenous inoculation. In contrast, immune syphilitic rabbits cleared the virulent treponemes within 1 to 2 hours. Rabbits with passive humoral immunity to T. pallidum (after the transfer of 70 ml of immune serum) showed a similar clearance rate to that of the immune rabbits. Rabbits previously treated with BCG and with passive humoral immunity did not show a synergistic enhanced clearance rate, it being similar to that of immune rabbits.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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