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. 1980 Jan;27(1):271–275. doi: 10.1128/iai.27.1.271-275.1980

Detection of a fibroblast proliferation inhibitory factor from Capnocytophaga sputigena.

R H Stevens, M N Sela, J Shapira, B F Hammond
PMCID: PMC550756  PMID: 7358430

Abstract

The addition of a sonic extract of Capnocytophaga sputigena to the culture fluid to human fibroblasts resulted in an inhibition of cell proliferation. The inhibition was dose-related (200 micrograms/ml caused a 90% inhibition, and 1,000 micrograms/ml caused a complete cessation of growth). The growth inhibition was not due to alterations in culture medium, pH or ionic strength, or to the effects of the C. sputigena lipopolysaccharide.

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Selected References

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