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. 1980 Feb;27(2):297–301. doi: 10.1128/iai.27.2.297-301.1980

In vitro synthesis of anti-mycobacterial antibodies in biopsies from skin lesions of leprosy patients.

R F Lai A Fat, J Chan Pin Jin, R van Furth, M Harboe
PMCID: PMC550764  PMID: 6991410

Abstract

To demonstrate local synthesis of anti-Mycobacterium leprae antibodies, biopsies from skin lesions of leprosy patients were cultured in vitro in a medium containing 14C-labeled lysine and isoleucine, and the culture fluids were analyzed by crossed immunoelectrophoresis with intermediate gel and autoradiography. The results show that anti-M. leprae antibodies were synthesized in vitro in the biopsies from the skin lesions of leprosy patients and that the specificity of the locally produced antibodies varied from patient to patient.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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