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. 1980 Feb;27(2):351–354. doi: 10.1128/iai.27.2.351-354.1980

Shift in the prevalent human rotavirus detected by ribonucleic acid segment differences.

R T Espejo, O Muñóz, F Serafin, P Romero
PMCID: PMC550771  PMID: 6247273

Abstract

Rotavirus was purified from nine patients hospitalized with acute gastroenteritis from October to December, 1978, in Mexico City. Analysis of their ribonucleic acids by gel electrophoresis showed the presence of two distinct patterns (2s and 22) which had been observed in 1977, but which now were found in a very different proportion: the pattern called 2s, observed in only 11% (6 of 52) of the patients in 1977, was found in 90% (8 of 9) of the patients in 1978. Improvements in the electrophoretic method allowed us to observe differences in the migration of up to seven segments between the two patterns and to distinguish small differences in one or two segments within either of the two ribonucleic acid patterns.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Chrystie I. L., Totterdell B. M., Banatvala J. E. Asymptomatic endemic rotavirus infections in the newborn. Lancet. 1978 Jun 3;1(8075):1176–1178. doi: 10.1016/S0140-6736(78)90967-4. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Espejo R. T., Calderon E., Gonzalez N. Distinct reovirus-like agents associated with acute infantile gastroenteritis. J Clin Microbiol. 1977 Nov;6(5):502–506. doi: 10.1128/jcm.6.5.502-506.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Espejo R. T., Calderón E., González N., Salomon A., Martuscelli A., Romero P. Presence of two distinct types of rotavirus in infants and young children hospitalized with acute gastroenteritis in Mexico City, 1977. J Infect Dis. 1979 Apr;139(4):474–477. doi: 10.1093/infdis/139.4.474. [DOI] [PubMed] [Google Scholar]
  4. Flewett T. H., Thouless M. E., Pilfold J. N., Bryden A. S., Candeias J. A. More serotypes of human rotavirus. Lancet. 1978 Sep 16;2(8090):632–632. doi: 10.1016/s0140-6736(78)92854-4. [DOI] [PubMed] [Google Scholar]
  5. Kalica A. R., Sereno M. M., Wyatt R. G., Mebus C. A., Chanock R. M., Kapikian A. Z. Comparison of human and animal rotavirus strains by gel electrophoresis of viral RNA. Virology. 1978 Jun 15;87(2):247–255. doi: 10.1016/0042-6822(78)90130-7. [DOI] [PubMed] [Google Scholar]
  6. Palese P. The genes of influenza virus. Cell. 1977 Jan;10(1):1–10. doi: 10.1016/0092-8674(77)90133-7. [DOI] [PubMed] [Google Scholar]
  7. Rodriguez W. J., Kim H. W., Brandt C. D., Yolken R. H., Arrobio J. O., Kapikian A. Z., Chanock R. M., Parrott R. H. Sequential enteric illnesses associated with different rotavirus serotypes. Lancet. 1978 Jul 1;2(8079):37–37. doi: 10.1016/s0140-6736(78)91339-9. [DOI] [PubMed] [Google Scholar]
  8. Smith R. E., Zweerink H. J., Joklik W. K. Polypeptide components of virions, top component and cores of reovirus type 3. Virology. 1969 Dec;39(4):791–810. doi: 10.1016/0042-6822(69)90017-8. [DOI] [PubMed] [Google Scholar]
  9. Zissis G., Lambert J. P. Different serotypes of human rotaviruses. Lancet. 1978 Jan 7;1(8054):38–39. doi: 10.1016/s0140-6736(78)90380-x. [DOI] [PubMed] [Google Scholar]

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