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. 1980 Apr;28(1):6–10. doi: 10.1128/iai.28.1.6-10.1980

Inhibition by interferon of Sendai virus cytolysis.

T Sato, Y Tomita, T Kuwata
PMCID: PMC550885  PMID: 6155349

Abstract

Treatment of HeLa cells with human interferons inhibited 51Cr release from cells induced by ultraviolet-inactivated Sendai virus. The inhibitory effect became apparent about 6 h after interferon treatment and persisted for 24 to 48 h. In the interferon-treated cells, the cytolysis was inhibited within 10 min after adding virus and the inhibitory action was suppressed by the treatment of the cells with cycloheximide. Mock interferon and mouse interferon did not inhibit the cytolysis and antiinterferon serum neutralized the effect of interferon. All these findings indicate that Sendai virus-induced cytolysis is inhibited by interferon per se. However, interferon did not have any influence on Sendai virus hemolysis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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