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. 1980 Apr;28(1):295–297. doi: 10.1128/iai.28.1.295-297.1980

Gamma-irradiated scrub typhus immunogens: analysis for residual, replicating rickettsiae.

G H Eisenberg Jr, J V Osterman, E H Stephenson
PMCID: PMC550928  PMID: 6769819

Abstract

Scrub typhus immunogens that received inadequate gamma radiation contained residual, viable rickettsiae. The presence of these organisms in the host was masked by the rapid immune response elicited by the large number of inactivated rickettsiae. Transfer of homogenized spleen cells from immunized mice to normal syngeneic recipients provided a sensitive technique for the detection of these viable, replicating organisms.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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