Skip to main content
PMC home page
Infection and Immunity logoLink to Infection and Immunity
. 1980 May;28(2):630–632. doi: 10.1128/iai.28.2.630-632.1980

Depressed malarial immunity in pregnant mice.

A A van Zon, W M Eling
PMCID: PMC550981  PMID: 6995314

Abstract

A proportion of mice solidly immune to the rodent malaria parasite Plasmodium berghei exhibited a pregnancy-associated depressed immunity with a transient or even lethal recrudescence.

Full text

PDF
630

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BRUCE-CHWATT L. J. Malaria in African infants and children in Southern Nigeria. Ann Trop Med Parasitol. 1952 Sep;46(2):173–200. doi: 10.1080/00034983.1952.11685522. [DOI] [PubMed] [Google Scholar]
  2. Barg M., Burton R. C., Smith J. A., Luckenbach G. A., Decker J., Mitchell G. F. Effects of placental tissue on immunological responses. Clin Exp Immunol. 1978 Dec;34(3):441–448. [PMC free article] [PubMed] [Google Scholar]
  3. Bray R. S., Anderson M. J. Falciparum malaria and pregnancy. Trans R Soc Trop Med Hyg. 1979;73(4):427–431. doi: 10.1016/0035-9203(79)90170-6. [DOI] [PubMed] [Google Scholar]
  4. CANNON D. S. Malaria and prematurity in the western region of Nigeria. Br Med J. 1958 Oct 11;2(5101):877–878. doi: 10.1136/bmj.2.5101.877. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Clarke F. M., Morton H., Clunie G. J. Detection and separation of two serum factors responsible for depression of lymphocyte activity in pregnancy. Clin Exp Immunol. 1978 May;32(2):318–323. [PMC free article] [PubMed] [Google Scholar]
  6. Czokało M., Wiśniewski L. Inhibition of blastic transformation and immunoglobulin release in lymphocytes cultured in the presence of alpha-fetoprotein (AFP). Exp Pathol (Jena) 1979;17(3):176–180. doi: 10.1016/s0014-4908(79)80026-5. [DOI] [PubMed] [Google Scholar]
  7. Eling W. M. Plasmodium berghei: effect of antithymocyte serum on induction of immunity in the mouse. Exp Parasitol. 1979 Jun;47(3):403–409. doi: 10.1016/0014-4894(79)90093-6. [DOI] [PubMed] [Google Scholar]
  8. Eling W. M. Plasmodium berghei: premunition, sterile immunity, and loss of immunity in mice. Exp Parasitol. 1980 Feb;49(1):89–96. doi: 10.1016/0014-4894(80)90060-0. [DOI] [PubMed] [Google Scholar]
  9. Eling W. Fading of malaria immunity in mice. Tropenmed Parasitol. 1978 Mar;29(1):77–84. [PubMed] [Google Scholar]
  10. Eling W. Survival of parasites in mice immunized against Plasmodium berghei. Tropenmed Parasitol. 1978 Jun;29(2):204–209. [PubMed] [Google Scholar]
  11. Exon P. D., Dixon K. Immunological responses in pregnancy. Br Med J. 1972 Nov 11;4(5836):361–362. doi: 10.1136/bmj.4.5836.361-c. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Fabris N., Piantanelli L., Muzzioli M. Differential effect of pregnancy or gestagens on humoral and cell-mediated immunity. Clin Exp Immunol. 1977 May;28(2):306–314. [PMC free article] [PubMed] [Google Scholar]
  13. Gilles H. M., Lawson J. B., Sibelas M., Voller A., Allan N. Malaria, anaemia and pregnancy. Ann Trop Med Parasitol. 1969 Jun;63(2):245–263. doi: 10.1080/00034983.1969.11686625. [DOI] [PubMed] [Google Scholar]
  14. ITO T., HOSHINO T. Studies of the influences of pregnancy and lactation on the thymus in the mouse. Z Zellforsch Mikrosk Anat. 1962;57:667–678. doi: 10.1007/BF00410229. [DOI] [PubMed] [Google Scholar]
  15. Karmali R. A., Lauder I., Horrobin D. F. Letter: Prolactin and the immune response. Lancet. 1974 Jul 13;2(7872):106–107. doi: 10.1016/s0140-6736(74)91670-5. [DOI] [PubMed] [Google Scholar]
  16. Kenny J. F., Diamond M. Immunological responsiveness to Escherichia coli during pregnancy. Infect Immun. 1977 Apr;16(1):174–180. doi: 10.1128/iai.16.1.174-180.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Lewis R., Lauersen N. H., Birnbaum S. Malaria associated with pregnancy. Obstet Gynecol. 1973 Nov;42(5):696–700. [PubMed] [Google Scholar]
  18. Maroni E. S., de Sousa M. A. The lymphoid organs during pregnancy in the mouse. A comparison between a syngeneic and an allogeneic mating. Clin Exp Immunol. 1973 Jan;13(1):107–124. [PMC free article] [PubMed] [Google Scholar]
  19. McGREGOR I. A., SMITH D. A. A health, nutrition and parasitological survey in a rural village (Keneba) in west Kiang, Gambia. Trans R Soc Trop Med Hyg. 1952 Jul;46(4):403–427. doi: 10.1016/0035-9203(52)90058-8. [DOI] [PubMed] [Google Scholar]
  20. Menon R. Pregnancy and malaria. Med J Malaya. 1972 Dec;27(2):115–119. [PubMed] [Google Scholar]
  21. Morton H., Hegh V., Clunie G. J. Immunosuppression detected in pregnant mice by rosette inhibition test. Nature. 1974 May 31;249(456):459–460. doi: 10.1038/249459a0. [DOI] [PubMed] [Google Scholar]
  22. Morton H., Hegh V., Clunie G. J. Studies of the rosette inhibition test in pregnant mice: evidence of immunosuppression? Proc R Soc Lond B Biol Sci. 1976 Jun 30;193(1113):413–419. doi: 10.1098/rspb.1976.0054. [DOI] [PubMed] [Google Scholar]
  23. Murgita R. A., Goidl E. A., Kontianen S., Wigzell H. alpha-Fetoprotein induces suppressor T cells in vitro. Nature. 1977 May 19;267(5608):257–259. doi: 10.1038/267257a0. [DOI] [PubMed] [Google Scholar]
  24. Murgita R. A. The immunosuppressive role of alpha-fetoprotein during pregnancy. Scand J Immunol. 1976;5(9):1003–1014. doi: 10.1111/j.1365-3083.1976.tb03052.x. [DOI] [PubMed] [Google Scholar]
  25. Pingoud E. Malariaplasmodien im Blute von Schwangeren und Nichtschwageren in Abeokuta (West-Nigeria) Z Tropenmed Parasitol. 1969 Sep;20(3):279–287. [PubMed] [Google Scholar]
  26. SPITZ A. J. Malaria infection of the placenta and its influence on the incidence of prematurity in eastern Nigeria. Bull World Health Organ. 1959;21:242–244. [PMC free article] [PubMed] [Google Scholar]
  27. Siiteri P. K., Febres F., Clemens L. E., Chang R. J., Gondos B., Stites D. Progesterone and maintenance of pregnancy: is progesterone nature's immunosuppressant? Ann N Y Acad Sci. 1977 Mar 11;286:384–397. doi: 10.1111/j.1749-6632.1977.tb29431.x. [DOI] [PubMed] [Google Scholar]
  28. Stimson W. H. Studies on the immunosuppressive properties of a pregnancy-associated alpha-macroglobulin. Clin Exp Immunol. 1976 Aug;25(2):199–206. [PMC free article] [PubMed] [Google Scholar]
  29. Than G. N., Csaba I. F., Szabó D. G. Letter: An antigen associated with pregnancy. Lancet. 1974 Dec 28;2(7896):1578–1579. doi: 10.1016/s0140-6736(74)90333-x. [DOI] [PubMed] [Google Scholar]
  30. Von Schoultz B., Stigbrand T., Tärnvik A. Inhibition of PHA-induced lymphocyte stimulation by the pregnancy zone protein. FEBS Lett. 1973 Dec 15;38(1):23–26. doi: 10.1016/0014-5793(73)80503-4. [DOI] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES