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. 1980 Jun;28(3):853–859. doi: 10.1128/iai.28.3.853-859.1980

Microflora and chemical composition of dental plaque from subjects with hereditary fructose intolerance.

C I Hoover, E Newbrun, G Mettraux, H Graf
PMCID: PMC551029  PMID: 7399699

Abstract

We compared the microbiological and chemical composition of dental plaque from subjects with hereditary fructose intolerance who restrict their dietary sugar intake with that of control subjects who do not. The two groups showed no significant differences in chemical composition of plaque: the mean protein, carbohydrate, calcium, magnesium, and phosphate contents were similar. Dental plaque from both groups contained similar numbers of total colony-forming units per microgram of plaque protein, and Streptococcus sanguis, an indigenous nonpathogen, was isolated with equal frequency from plaque samples of both groups. However, potentially odontopathic Streptococcus mutans and Lactobacillus were isolated three to four times more frequently from plaque samples of control subjects than from plaque samples of subjects with hereditary fructose intolerance. Clearly, diet (sucrose in particular) influences the colonization and multiplication of specific cariogenic organisms in dental plaque.

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Selected References

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