Table 3.
On-treatment predictors of response
| Complete Virological Response^ | Virological Response° | |||||
|---|---|---|---|---|---|---|
| Yes | No | p-value1 | Yes | No | p-value1 | |
| HDV RNA 4 week slope (GE log10/mL/week)* | −0.35±0.15 | −0.24±0.08 | 0.43 | −0.35±0.15 | −0.24±0.09 | 0.75 |
| HDV RNA week 12 decline (GE log10 /mL)* | 3.6±3.3 | 1.3±1.6 | 0.31 | 3.0±2.5 | 0.8±1.8 | 0.20 |
| HBsAg 4 week slope (IU log10/mL/week)* | −0.04±0.08 | 0.03±0.04 | 0.12 | −0.02±0.06 | 0.03±0.05 | 0.22 |
| HBsAg week 12 decline (IU log10/mL)* | 1.7±1.8 | 0.06±0.5 | 0.07 | 1.5±1.3 | −0.1±0.2 | 0.05 |
Mann-Whitney test
Mean ±SD
Complete Virological Response = Undetectable HDV RNA in serum and seroconversion of HBsAg
Virological Response = Undetectable HDV RNA in serum