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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Shock. 2017 Aug;48(2):159–167. doi: 10.1097/SHK.0000000000000854

Table 1. Anticoagulation effects on mortality in DIC.

APACHE II <20 (n=317) APACHE II 20-30 (n=511) APACHE II >30 (n=317)
Mortality without anti-coagulation (anti-thrombin +/- recombinant human thrombomodulin) (%)
Adjusted OR 		28.3
1.00		 47
1.00		 64.5
1.00
Mortality with anti-coagulation (anti-thrombin +/- recombinant human thrombomodulin)(%)
Adjusted OR (95% CI) 		21.8
0.64 (0.34-1.22)		 35.5
0.52 (0.33-0.82)*		 61.3
0.75 (0.43-1.28)

Mortality rates and adjusted odds ratio for death comparing patients with and without anticoagulation in overt DIC (defined as JAAM score ≥4 and ISTH score ≥5) in the J-SEPTIC DIC study.