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. 1980 Oct;30(1):147–149. doi: 10.1128/iai.30.1.147-149.1980

Activation of the alternative complement pathway by Histoplasma capsulatum.

W D Ratnoff, J M Pepple, J A Winkelstein
PMCID: PMC551289  PMID: 7439970

Abstract

The present study was performed to determine whether Histoplasma capsulatum (yeast phase) is able to activate the alternative complement pathway. H. capsulatum yeasts were shown to consume C3 in C4-deficient guinea pig serum. Immunoelectrophoretic conversion of alternative pathway component factor B confirmed that C3 consumption was mediated by activation of the alternative pathway. These results demonstrate that H. capsulatum is able to activate the alternative complement pathway.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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