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Vasodilatory effects of acetylcholine (Ach) on noradrenaline (NA)-induced (10− 6 M) contraction of aortic strips either naïve or precontracted with carfilzomib (CFZ). *p < 0.05; **p < 0.01 and ***p < 0.001 in the comparison between the effects of Ach in presence or absence of CFZ.
