Abstract
Synergistic hemolysis of sheep erythrocytes caused by Staphylococcus aureus and Corynebacterium renale resulted from the combined action of extracellular staphylococcal sphingomyelinase C and a newly described extracellular agent of C. renale (renalin). The affinity of renalin for ceramide was considered to play a key role in causing hemolysis in erythrocytes in which ceramide had been generated through the action of sphingomyelinase C.
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