Table 3B. Univariate and multivariate Cox proportional hazard regression analysis-between clinicopathologic variables and OS.

Variables		Univariate			Multivariate
		HR	95% CI	P value	HR	95% CI	P value
T status	T1	1			1
	T2	1.613	1.160–2.242	0.005	1.700	1.207–2.395	0.002
	T3	2.142	1.341–3.422	0.001	2.059	1.232–3.441	0.006
ECE	ECE (−)	1			1
	ECE(+)	1.574	1.108–2.236	0.011	1.377	0.942–2.015	0.099
N2 stations	Single	1			1
	Multiple	1.542	1.155–2.058	0.003	1.217	0.874–1.695	0.245
Pathology	Adenocarcinoma	1			1
	Squamous carcinoma	1.176	0.852–1.624	0.324	1.355	0.966–1.899	0.078
	Adeno-squamous carcinoma	1.996	1.219–3.269	0.006	2.322	1.404–3.839	0.001
	others	1.251	0.700–2.234	0.450	1.353	0.754–2.429	0.311
LN Skip	LN skip	1			1
status	LN no skip	1.486	1.095–2.018	0.011	1.592	1.154–2.197	0.005
Positive	≤ 20.5%	1			1
N2 ratio	> 20.5%	1.515	1.134–2.023	0.005	1.491	1.052–2.113	0.025