Figure 7.
Interneuron ablation produces both convulsive and nonconvulsive seizures. Nonconvulsive and convulsive seizures were indistinguishable in the LFP recordings. The top and bottom seizures occurred ∼8 min apart in the same mouse. The first seizure (top) was associated with behavioral arrest and a gentle head nod side-to-side. The second seizure (bottom) was convulsive with forelimb clonus. Boxed regions are expanded below for both seizures to illustrate the similarities in waveforms during both high-frequency and large-amplitude periods of activity.