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. 2017 Apr 26;66(8):2137–2143. doi: 10.2337/db17-0070

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© 2017 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

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Gut dysbiosis is rebalanced through cationic polystyrene treatment. The microbiota in the ileum and feces of the mice described in Fig. 1 was examined. A: The abundances of phyla Firmicutes (Firm) and Bacteroidetes (Bact), species A. muciniphila (Akk), and class Gammaproteobacteria (γ-proteo) in the feces were detected by 16S rDNA-qPCR (n = 6 for each group). B: The bacteria population in the lumen of ileum was determined by high-throughput sequencing analysis (n = 5 for each group). UPGMA (unweighted pair-group method with arithmetic mean) clustering based on weighted unifrac distance of the top 10 relative abundant phyla. C: NMDS (non-metric multidimensional scaling) plot; every point shows one mouse, different colors signify different groups, and the stress = 0.127. D: The relative abundance of bacteria at phylum levels in the ileal lumen. E: The relative abundance of A. muciniphila in the ileal content. Ctrl, control.