. 2017 Apr 18;8(26):42510–42524. doi: 10.18632/oncotarget.17207

Table 1. EC₅₀s (μM) of 3 compounds in enzyme and cell based assays.

Compound	Enzyme EC⁵⁰ (μM)	Cell EC⁵⁰ (μM)	KD
7170
	18.03	13.32 ± 1.32	1.131 × 10⁻⁶
YL001
	1.18	14.27 ± 0.78	1.327 × 10⁻⁷
STLC
	2.52	1.46 ± 0.06	3.767 × 10⁻⁷

Enzymatic EC₅₀s were assessed in Eg5 ATPase activity and cellular EC₅₀s were evaluated on HeLa cell line. KD values were calculated with SPR Biacore T200. STLC was used as a control.

Table 1. EC50s (μM) of 3 compounds in enzyme and cell based assays.

Table 1. EC₅₀s (μM) of 3 compounds in enzyme and cell based assays.