Table 1. Kinetic parameters for the incorporation of dATP and 3-Eth-5-NITP opposite an abasic site catalyzed by human pol δ and pol η.

Nucleotide	Polymerase	Km(μM)	kcat(sec-1)	kcat/Km(M-1sec-1)
dATP	pol δ	560 ± 180	0.0031 ± 0.0004	5.5 ± 1.2
dATP	pol η	46 ± 11	0.12 ± 0.01	2,610 ± 550
3-Eth-5-NITP	pol δ	2.0 ± 0.4	0.013 ± 0.001	6,400 ± 900
3-Eth-5-NITP	pol η	3.8 ± 1.2	0.26 ± 0.06	68,420 ± 2,500