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BCG-GFP uptake by alveolar and monocyte-derived macrophages after 18 h. Uptake (percentage of cells positive for GFP by flow cytometry) is depicted for subjects (n=7) following 18 h of infection. Uptake by macrophages with and without exposure to 10% cigarette smoke extract (CSE) from individual donors is depicted by joined lines. The horizontal line represents the median value for all individuals.
