Table 1.
Summary characteristics of baseline demographic and chemistry biomarker covariates among participants who received IV or SC VRC01 in HVTN104 (n = 84).
| Covariate | Median (min – max) or frequency |
|---|---|
| Age (years) | 27 (18–50) |
| Female gender (% of females) | 42 (50%) |
| Weight (kg) | 72 (53–114) |
| Body mass index (kg/m) | 24.89 (18.52–37.64) |
| Creatinine | 0.83 (0.48–1.31) |
| Creatinine clearance (CrCL, mL/min) | 125.9 (68.48–253.70) |
| Alkaline phosphatase (ALP, units/L) | 63 (30–117) |
| Alkaline aminotransferase (ALT, units/L) | 17 (6–73) |
| Aspartate aminotransferase (AST, units/L) | 18 (12–37) |
| Hemoglobin (g/dl) | 14 (11.2–17.6) |
| Platelets (103/mm3) | 241 (135–411) |
| Lymphocyte count (cells/mm3) | 1945 (866–3610) |
| Neutrophil count (cells/mm3) | 3775 (1279–8208) |
| White blood cell count (WBC, 103/mm3) | 6.55 (2.8–12) |