Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Fluorescein and scheme for a fluorescein-bearing alkylammoniomethyltrifluoroborate 2. Reagent and conditions: (a) 1.2 eq. 4-Azidobutan-1-amine, DMF, RT, 12h; (b) N,N-Dimethyl-N-Propargyl-N-Methyltrifluoroborate, 1.0M CuSO4 5 H2O, 1.0 M Sodium ascorbate, DMF, 50°C, 6 hours. Radiolabeling: 2 is added to a water-DMSO mixture of pyridazine-HCl 1.25 M, pH 2.5 and [18F]- fluoride ion. It is heated at 50-100ºC for 10-30 min.
