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. 1982;1(2):161–165. doi: 10.1002/j.1460-2075.1982.tb01141.x

Vimentin and keratin intermediate filament systems in cultured PtK2 epithelial cells are interrelated.

M W Klymkowsky
PMCID: PMC553014  PMID: 6201355

Abstract

Certain cultured epithelial cells contain separate vimentin and keratin-type intermediate filament networks. The intracellular injection of monoclonal antibodies directed against either vimentin or keratin filaments into PtK2 cultured epithelial cells specifically disrupted the organization of both filament types. Neither antibody had any effect when injected into cells which, while containing vimentin or keratin filaments, lacked the specific filament type which that antibody recognized. These experiments suggest that keratin and vimentin filament networks are associated in some way with one another.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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