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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Xenobiotica. 2016 Mar 21;47(1):1–10. doi: 10.3109/00498254.2016.1156784

Table 2.

Analysis of differences in hepatic BPA glucuronidation activities associated with liver donor demographics and UGT genotypes.

BPA glucuronidation rate
(nmoles/min/mg protein)
Variable Group n Median Interquartile range P value
Gender Male 35 2.4 1.2 – 3.8 0.11a
Female 11 1.8 0.6 – 3.1
Drinks (per week) <14 27 1.8 0.8 – 3.6 0.46a
14 or more 12 2.3 1.7 – 2.8
Smoking Yes 15 2.0 1.1 – 3.1 0.70a
No 25 2.3 1.0 – 3.7
UGT1A1*28 *1/*1 21 2.6 1.5 – 4.0 0.51b
*1/*28 13 1.6 0.9 – 3.5
*28/*28 6 2.4 1.2 – 3.5
UGT1A9*22 *1/*1 16 2.4 1.2 – 3.5 0.012b
*1/*22 18 1.7 1.0 – 2.8
*22/*22 6 4.4 3.2 – 4.8
UGT2B15*2 *1/*1 8 3.1 2.4 – 5.2 0.23b
*1/*2 25 1.8 0.9 – 3.4
*2/*2 13 2.0 1.2 – 3.0
a

Rank sum test

b

Kruskal-Wallis one way analysis of variance on ranks.