Dear Editor,
Thanks for your interest in our scientific article Midazolam, a new more potent benzodiazepine compared with diazepam as sedative during spinal analgesia – a randomised study [1]. Bupivacaine isobaric 0.5% solution can be used to produce predictable level of subarachnoid block tailored to the needs of the patients [2]. Haemodynamic changes can be prevented with preload of one litre intravenous colloids prior to subarachnoid block. Sedation during spinal analgesia is desirable demand by majority of the patients was confirmed in our pilot study [3]. Sedation during high spinal >T4 level needs careful approach and monitoring of the patients irrespective of the sedative drug to be used. Our study included patients undergoing surgery to the lower abdomen, perineum or legs under spinal analgesia. The suggestions made by Lt Col KC Khanduri are practised by all the anaesthesiologists during regional block techniques of anaesthesia in service hospitals and civil medical institutions.
References
- 1.Suriz Yudhvir, Larnba Midazolam NS. A new more potent benzodiazepine, compared with diazepam as sedative during spinal analgesia. A randornised double blind study MJAFI. 2000;56:29–32. doi: 10.1016/S0377-1237(17)30086-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Bannister J, McClure JH, Wildsmith JAW. Effect of glucose concentration on the intrathecal spread of 0.5% bupivacaine. Brit J Anaesth. 1990;64:232–234. doi: 10.1093/bja/64.2.232. [DOI] [PubMed] [Google Scholar]
- 3.Suri Yudhvir, Lamba NS. Pilot study: sedation during spinal analgesia(Unpublished).