Figure 5. LEC cells stably maintained the selectivity for stimulus-environment conjunction during the stimulus-free period.
(A) Example of fluctuations of binned firing rates (FR) of a cell across the 9 s interval during each of six trial blocks. The degree of FR fluctuation was marginal across time bins in each trial block (‘Within’, rows) while FR greatly changed across six blocks (‘Between’, columns) as evident in the difference in Kullback-Leibler divergence from a uniform distribution (KLD, right). (B) Distribution of the difference between the Between-KLD and Within-KLD. (C) Cumulative distribution of the Within- (black) and Between- (red) KLD. (D) Difference in the proportion of cells whose ITI firing rates were judged as selective for at least one of three task features depending on the bin size. The same criteria were applied to averaged firing rates in one 9 s bin (1), four 2.25 s bins (1/4), or eight 1.125 s bins (1/8) covering the 9 s ITI. (E) The proportion of selectivity categories (see Table 4) of firing rates during a series of eight 1.125 s bins during the 9 s ITI. The 8th bin was the closest to CS onset.