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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Leukemia. 2016 Dec 23;31(8):1715–1726. doi: 10.1038/leu.2016.379

Table 1.

IC50 values for pan-PIM inhibitors as determined by PIM enzyme assays.

PIM inhibitors PIM1 IC50 (nM) PIM2 IC50 (nM) PIM3 IC50 (nM) Manufacturer
SGI-1776 7 363 69 SuperGen
JP11413 38 0.6 9 Jasco
JP11416 36 1 6 Jasco
JP11644 32 0.7 6 Jasco
JP11646 24 0.5 1 Jasco
JP11660 42 2 4 Jasco
JP11662 50 9 4 Jasco