Table 2.
Prevalence of inherited hemoglobin disorders among a representative sample of children 12–59 months of age in Yaoundé and Douala, Cameroon 1.
| Urban Total | Yaoundé | Douala | ||
|---|---|---|---|---|
| Any Hb S or alpha-globin 2 deletion | 42.9 (37.4–48.4) | 48.9 (39.7–58.1) | 37.1 (30.1–44.0) | |
| Sickle cell disease or trait 3 | ||||
| HbSS | 1.6 (0.2–3.0) | 2.7 (0.1–5.3) | 0.6 (0–1.9) | |
| HbAS | 13.7 (9.7–17.8) | 12.6 (6.3–18.9) | 14.8 (9.1–20.5) | |
| α+-thalassemia 2 | ||||
| Homozygous (–α/–α) | 3.1 (1.1–5.2) | 4.9 (1.2–8.6) | 1.4 (0–3.5) | |
| Heterozygous (–α/αα) | 30.6 (25.4–35.8) | 37.0 (27.7–46.4) | 24.4 (18.9–29.9) | |
| Other Hb conditions 3 | ||||
| Increased F | 4.7 (2.7–6.6) | 5.5 (2.5–8.4) | 3.9 (1.2–6.7) |
1 Values are the mean (95% CI). Hb, hemoglobin. 2 n = 288. 3 n = 295.