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. 1987 May;6(5):1145–1154. doi: 10.1002/j.1460-2075.1987.tb02347.x

The nerve growth factor: thirty-five years later.

R Levi-Montalcini
PMCID: PMC553912  PMID: 3301324

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Selected References

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  1. Alemà S., Casalbore P., Agostini E., Tatò F. Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene. Nature. 1985 Aug 8;316(6028):557–559. doi: 10.1038/316557a0. [DOI] [PubMed] [Google Scholar]
  2. Aloe L., Alleva E., Böhm A., Levi-Montalcini R. Aggressive behavior induces release of nerve growth factor from mouse salivary gland into the bloodstream. Proc Natl Acad Sci U S A. 1986 Aug;83(16):6184–6187. doi: 10.1073/pnas.83.16.6184. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Aloe L., Cozzari C., Calissano P., Levi-Montalcini R. Somatic and behavioral postnatal effects of fetal injections of nerve growth factor antibodies in the rat. Nature. 1981 Jun 4;291(5814):413–415. doi: 10.1038/291413a0. [DOI] [PubMed] [Google Scholar]
  4. Aloe L., Cozzari C., Levi-Montalcini R. Cyclocytidine-induced release of nerve growth factor from mouse submandibular glands enhances regeneration of sympathetic fibers in adult mice. Brain Res. 1985 Apr 22;332(2):259–265. doi: 10.1016/0006-8993(85)90595-5. [DOI] [PubMed] [Google Scholar]
  5. Aloe L., Levi-Montalcini R. Comparative studies on testosterone and L-thyroxine effects on the synthesis of nerve growth factor in mouse submaxillary salivary glands. Exp Cell Res. 1980 Jan;125(1):15–22. doi: 10.1016/0014-4827(80)90183-4. [DOI] [PubMed] [Google Scholar]
  6. Aloe L., Levi-Montalcini R. Mast cells increase in tissues of neonatal rats injected with the nerve growth factor. Brain Res. 1977 Sep 16;133(2):358–366. doi: 10.1016/0006-8993(77)90772-7. [DOI] [PubMed] [Google Scholar]
  7. Aloe L., Levi-Montalcini R. Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor. Proc Natl Acad Sci U S A. 1979 Mar;76(3):1246–1250. doi: 10.1073/pnas.76.3.1246. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Aloe L., Mugnaini E., Levi-Montalcini R. Light and electron microscopic studies on the excessive growth of sympathetic ganglia in rats injected daily from birth with 6-OHDA and NGF. Arch Ital Biol. 1975 Dec;113(4):326–353. [PubMed] [Google Scholar]
  9. Angeletti P. U., Levi-Montalcini R. Sympathetic nerve cell destruction in newborn mammals by 6-hydroxydopamine. Proc Natl Acad Sci U S A. 1970 Jan;65(1):114–121. doi: 10.1073/pnas.65.1.114. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Angeletti R. H., Bradshaw R. A. Nerve growth factor from mouse submaxillary gland: amino acid sequence. Proc Natl Acad Sci U S A. 1971 Oct;68(10):2417–2420. doi: 10.1073/pnas.68.10.2417. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Bing J., Poulsen K., Hackenthal E., Rix E., Taugner R. Renin in the submaxillary gland: a review. J Histochem Cytochem. 1980 Aug;28(8):874–880. doi: 10.1177/28.8.7003007. [DOI] [PubMed] [Google Scholar]
  12. Bradshaw R. A. Nerve growth factor. Annu Rev Biochem. 1978;47:191–216. doi: 10.1146/annurev.bi.47.070178.001203. [DOI] [PubMed] [Google Scholar]
  13. Bruni A., Bigon E., Boarato E., Mietto L., Leon A., Toffano G. Interaction between nerve growth factor and lysophosphatidylserine on rat peritoneal mast cells. FEBS Lett. 1982 Feb 22;138(2):190–192. doi: 10.1016/0014-5793(82)80438-9. [DOI] [PubMed] [Google Scholar]
  14. Burstein D. E., Greene L. A. Nerve growth factor has both mitogenic and antimitogenic activity. Dev Biol. 1982 Dec;94(2):477–482. doi: 10.1016/0012-1606(82)90364-5. [DOI] [PubMed] [Google Scholar]
  15. COHEN S. Purification and metabolic effects of a nerve growth-promoting protein from snake venom. J Biol Chem. 1959 May;234(5):1129–1137. [PubMed] [Google Scholar]
  16. Calissano P., Cattaneo A., Biocca S., Aloe L., Mercanti D., Levi-Montalcini R. The nerve growth factor. Established findings and controversial aspects. Exp Cell Res. 1984 Sep;154(1):1–9. doi: 10.1016/0014-4827(84)90663-3. [DOI] [PubMed] [Google Scholar]
  17. Campenot R. B. Development of sympathetic neurons in compartmentalized cultures. Il Local control of neurite growth by nerve growth factor. Dev Biol. 1982 Sep;93(1):1–12. doi: 10.1016/0012-1606(82)90232-9. [DOI] [PubMed] [Google Scholar]
  18. Cohen S., Levi-Montalcini R. A NERVE GROWTH-STIMULATING FACTOR ISOLATED FROM SNAKE VENOM. Proc Natl Acad Sci U S A. 1956 Sep;42(9):571–574. doi: 10.1073/pnas.42.9.571. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Cohen S., Levi-Montalcini R., Hamburger V. A NERVE GROWTH-STIMULATING FACTOR ISOLATED FROM SARCOM AS 37 AND 180. Proc Natl Acad Sci U S A. 1954 Oct;40(10):1014–1018. doi: 10.1073/pnas.40.10.1014. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Doolittle R. F., Hunkapiller M. W., Hood L. E., Devare S. G., Robbins K. C., Aaronson S. A., Antoniades H. N. Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor. Science. 1983 Jul 15;221(4607):275–277. doi: 10.1126/science.6304883. [DOI] [PubMed] [Google Scholar]
  21. Doupe A. J., Landis S. C., Patterson P. H. Environmental influences in the development of neural crest derivatives: glucocorticoids, growth factors, and chromaffin cell plasticity. J Neurosci. 1985 Aug;5(8):2119–2142. doi: 10.1523/JNEUROSCI.05-08-02119.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Doupe A. J., Patterson P. H., Landis S. C. Small intensely fluorescent cells in culture: role of glucocorticoids and growth factors in their development and interconversions with other neural crest derivatives. J Neurosci. 1985 Aug;5(8):2143–2160. doi: 10.1523/JNEUROSCI.05-08-02143.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Downward J., Yarden Y., Mayes E., Scrace G., Totty N., Stockwell P., Ullrich A., Schlessinger J., Waterfield M. D. Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. Nature. 1984 Feb 9;307(5951):521–527. doi: 10.1038/307521a0. [DOI] [PubMed] [Google Scholar]
  24. Ebendal T., Larhammar D., Persson H. Structure and expression of the chicken beta nerve growth factor gene. EMBO J. 1986 Jul;5(7):1483–1487. doi: 10.1002/j.1460-2075.1986.tb04386.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Ebendal T., Olson L., Seiger A., Hedlund K. O. Nerve growth factors in the rat iris. Nature. 1980 Jul 3;286(5768):25–28. doi: 10.1038/286025a0. [DOI] [PubMed] [Google Scholar]
  26. Edwards R. H., Selby M. J., Rutter W. J. Differential RNA splicing predicts two distinct nerve growth factor precursors. 1986 Feb 27-Mar 5Nature. 319(6056):784–787. doi: 10.1038/319784a0. [DOI] [PubMed] [Google Scholar]
  27. Francke U., de Martinville B., Coussens L., Ullrich A. The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. Science. 1983 Dec 16;222(4629):1248–1251. doi: 10.1126/science.6648531. [DOI] [PubMed] [Google Scholar]
  28. Gnahn H., Hefti F., Heumann R., Schwab M. E., Thoenen H. NGF-mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: evidence for a physiological role of NGF in the brain? Brain Res. 1983 Jul;285(1):45–52. doi: 10.1016/0165-3806(83)90107-4. [DOI] [PubMed] [Google Scholar]
  29. Goedert M., Otten U., Schäfer T., Schwab M., Thoenen H. Immunosympathectomy: lack of evidence for a complement-mediated cytotoxic mechanism. Brain Res. 1980 Nov 17;201(2):399–409. doi: 10.1016/0006-8993(80)91043-4. [DOI] [PubMed] [Google Scholar]
  30. Greene L. A., Liem R. K., Shelanski M. L. Regulation of a high molecular weight microtubule-associated protein in PC12 cells by nerve growth factor. J Cell Biol. 1983 Jan;96(1):76–83. doi: 10.1083/jcb.96.1.76. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Greene L. A., Shooter E. M. The nerve growth factor: biochemistry, synthesis, and mechanism of action. Annu Rev Neurosci. 1980;3:353–402. doi: 10.1146/annurev.ne.03.030180.002033. [DOI] [PubMed] [Google Scholar]
  32. Greene L. A., Tischler A. S. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A. 1976 Jul;73(7):2424–2428. doi: 10.1073/pnas.73.7.2424. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Gundersen R. W., Barrett J. N. Characterization of the turning response of dorsal root neurites toward nerve growth factor. J Cell Biol. 1980 Dec;87(3 Pt 1):546–554. doi: 10.1083/jcb.87.3.546. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Gundersen R. W., Barrett J. N. Neuronal chemotaxis: chick dorsal-root axons turn toward high concentrations of nerve growth factor. Science. 1979 Nov 30;206(4422):1079–1080. doi: 10.1126/science.493992. [DOI] [PubMed] [Google Scholar]
  35. Hamburger V., Brunso-Bechtold J. K., Yip J. W. Neuronal death in the spinal ganglia of the chick embryo and its reduction by nerve growth factor. J Neurosci. 1981 Jan;1(1):60–71. doi: 10.1523/JNEUROSCI.01-01-00060.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Hamburger V. Changing concepts in developmental neurobiology. Perspect Biol Med. 1975 Winter;18(2):162–178. doi: 10.1353/pbm.1975.0002. [DOI] [PubMed] [Google Scholar]
  37. Harper G. P., Barde Y. A., Burnstock G., Carstairs J. R., Dennison M. E., Suda K., Vernon C. A. Guinea pig prostate is a rich source of nerve growth factor. Nature. 1979 May 10;279(5709):160–162. doi: 10.1038/279160a0. [DOI] [PubMed] [Google Scholar]
  38. Harper G. P., Thoenen H. The distribution of nerve growth factor in the male sex organs of mammals. J Neurochem. 1980 Apr;34(4):893–903. doi: 10.1111/j.1471-4159.1980.tb09663.x. [DOI] [PubMed] [Google Scholar]
  39. Hefti F., Dravid A., Hartikka J. Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions. Brain Res. 1984 Feb 20;293(2):305–311. doi: 10.1016/0006-8993(84)91237-x. [DOI] [PubMed] [Google Scholar]
  40. Johnson E. M., Jr, Gorin P. D., Brandeis L. D., Pearson J. Dorsal root ganglion neurons are destroyed by exposure in utero to maternal antibody to nerve growth factor. Science. 1980 Nov 21;210(4472):916–918. doi: 10.1126/science.7192014. [DOI] [PubMed] [Google Scholar]
  41. Johnson E. M., Jr, Yip H. K. Central nervous system and peripheral nerve growth factor provide trophic support critical to mature sensory neuronal survival. 1985 Apr 25-May 1Nature. 314(6013):751–752. doi: 10.1038/314751a0. [DOI] [PubMed] [Google Scholar]
  42. Korsching S., Auburger G., Heumann R., Scott J., Thoenen H. Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J. 1985 Jun;4(6):1389–1393. doi: 10.1002/j.1460-2075.1985.tb03791.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Kromer L. F. Nerve growth factor treatment after brain injury prevents neuronal death. Science. 1987 Jan 9;235(4785):214–216. doi: 10.1126/science.3798108. [DOI] [PubMed] [Google Scholar]
  44. LEVI-MONTALCINI R., ANGELETTI P. U. Essential role of the nerve growth factor in the survival and maintenance of dissociated sensory and sympathetic embryonic nerve cells in vitro. Dev Biol. 1963 Mar;6:653–659. doi: 10.1016/0012-1606(63)90149-0. [DOI] [PubMed] [Google Scholar]
  45. LEVI-MONTALCINI R. Effects of mouse tumor transplantation on the nervous system. Ann N Y Acad Sci. 1952 Aug 8;55(2):330–344. doi: 10.1111/j.1749-6632.1952.tb26548.x. [DOI] [PubMed] [Google Scholar]
  46. LEVI-MONTALCINI R., MEYER H., HAMBURGER V. In vitro experiments on the effects of mouse sarcomas 180 and 37 on the spinal and sympathetic ganglia of the chick embryo. Cancer Res. 1954 Jan;14(1):49–57. [PubMed] [Google Scholar]
  47. LEVI-MONTALCINI R. The development to the acoustico-vestibular centers in the chick embryo in the absence of the afferent root fibers and of descending fiber tracts. J Comp Neurol. 1949 Oct;91(2):209-41, illust, incl 3 pl. doi: 10.1002/cne.900910204. [DOI] [PubMed] [Google Scholar]
  48. Lakshmanan J. Aggressive behavior in adult male mice elevates serum nerve growth factor levels. Am J Physiol. 1986 Apr;250(4 Pt 1):E386–E392. doi: 10.1152/ajpendo.1986.250.4.E386. [DOI] [PubMed] [Google Scholar]
  49. Levi-Montalcini R., Aloe L. Differentiating effects of murine nerve growth factor in the peripheral and central nervous systems of Xenopus laevis tadpoles. Proc Natl Acad Sci U S A. 1985 Oct;82(20):7111–7115. doi: 10.1073/pnas.82.20.7111. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Levi-Montalcini R., Aloe L., Mugnaini E., Oesch F., Thoenen H. Nerve growth factor induces volume increase and enhances tyrosine hydroxylase synthesis in chemically axotomized sympathetic ganglia of newborn rats. Proc Natl Acad Sci U S A. 1975 Feb;72(2):595–599. doi: 10.1073/pnas.72.2.595. [DOI] [PMC free article] [PubMed] [Google Scholar]
  51. Levi-Montalcini R., Booker B. DESTRUCTION OF THE SYMPATHETIC GANGLIA IN MAMMALS BY AN ANTISERUM TO A NERVE-GROWTH PROTEIN. Proc Natl Acad Sci U S A. 1960 Mar;46(3):384–391. doi: 10.1073/pnas.46.3.384. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Levi-Montalcini R., Booker B. EXCESSIVE GROWTH OF THE SYMPATHETIC GANGLIA EVOKED BY A PROTEIN ISOLATED FROM MOUSE SALIVARY GLANDS. Proc Natl Acad Sci U S A. 1960 Mar;46(3):373–384. doi: 10.1073/pnas.46.3.373. [DOI] [PMC free article] [PubMed] [Google Scholar]
  53. Levi-Montalcini R., Cohen S. IN VITRO AND IN VIVO EFFECTS OF A NERVE GROWTH-STIMULATING AGENT ISOLATED FROM SNAKE VENOM. Proc Natl Acad Sci U S A. 1956 Sep;42(9):695–699. doi: 10.1073/pnas.42.9.695. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Levi-Montalcini R. The nerve growth factor: its mode of action on sensory and sympathetic nerve cells. Harvey Lect. 1966;60:217–259. [PubMed] [Google Scholar]
  55. Lillien L. E., Claude P. Nerve growth factor is a mitogen for cultured chromaffin cells. Nature. 1985 Oct 17;317(6038):632–634. doi: 10.1038/317632a0. [DOI] [PubMed] [Google Scholar]
  56. Mazurek N., Weskamp G., Erne P., Otten U. Nerve growth factor induces mast cell degranulation without changing intracellular calcium levels. FEBS Lett. 1986 Mar 31;198(2):315–320. doi: 10.1016/0014-5793(86)80428-8. [DOI] [PubMed] [Google Scholar]
  57. Meier R., Becker-André M., Götz R., Heumann R., Shaw A., Thoenen H. Molecular cloning of bovine and chick nerve growth factor (NGF): delineation of conserved and unconserved domains and their relationship to the biological activity and antigenicity of NGF. EMBO J. 1986 Jul;5(7):1489–1493. doi: 10.1002/j.1460-2075.1986.tb04387.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  58. Menesini Chen M. G., Chen J. S., Levi-Montalcini R. Sympathetic nerve fibers ingrowth in the central nervous system of neonatal rodent upon intracerebral NGF injections. Arch Ital Biol. 1978 Jan;116(1):53–84. [PubMed] [Google Scholar]
  59. Mobley W. C., Rutkowski J. L., Tennekoon G. I., Buchanan K., Johnston M. V. Choline acetyltransferase activity in striatum of neonatal rats increased by nerve growth factor. Science. 1985 Jul 19;229(4710):284–287. doi: 10.1126/science.2861660. [DOI] [PubMed] [Google Scholar]
  60. Otten U., Schwab M., Gagnon C., Thoenen H. Selective induction of tyrosine hydroxylase and dopamine beta-hydroxylase by nerve growth factor: comparison between adrenal medulla and sympathetic ganglia of adult and newborn rats. Brain Res. 1977 Sep 16;133(2):291–303. doi: 10.1016/0006-8993(77)90765-x. [DOI] [PubMed] [Google Scholar]
  61. Paravicini U., Stoeckel K., Thoenen H. Biological importance of retrograde axonal transport of nerve growth factor in adrenergic neurons. Brain Res. 1975 Feb 7;84(2):279–291. doi: 10.1016/0006-8993(75)90982-8. [DOI] [PubMed] [Google Scholar]
  62. Pfenninger K. H., Johnson M. P. Nerve growth factor stimulates phospholipid methylation in growing neurites. Proc Natl Acad Sci U S A. 1981 Dec;78(12):7797–7800. doi: 10.1073/pnas.78.12.7797. [DOI] [PMC free article] [PubMed] [Google Scholar]
  63. Roszman T. L., Jackson J. C., Cross R. J., Titus M. J., Markesbery W. R., Brooks W. H. Neuroanatomic and neurotransmitter influences on immune function. J Immunol. 1985 Aug;135(2 Suppl):769s–772s. [PubMed] [Google Scholar]
  64. Scott J., Selby M., Urdea M., Quiroga M., Bell G. I., Rutter W. J. Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor. Nature. 1983 Apr 7;302(5908):538–540. doi: 10.1038/302538a0. [DOI] [PubMed] [Google Scholar]
  65. Seiler M., Schwab M. E. Specific retrograde transport of nerve growth factor (NGF) from neocortex to nucleus basalis in the rat. Brain Res. 1984 May 21;300(1):33–39. doi: 10.1016/0006-8993(84)91338-6. [DOI] [PubMed] [Google Scholar]
  66. Shelton D. L., Reichardt L. F. Studies on the expression of the beta nerve growth factor (NGF) gene in the central nervous system: level and regional distribution of NGF mRNA suggest that NGF functions as a trophic factor for several distinct populations of neurons. Proc Natl Acad Sci U S A. 1986 Apr;83(8):2714–2718. doi: 10.1073/pnas.83.8.2714. [DOI] [PMC free article] [PubMed] [Google Scholar]
  67. Sherr C. J., Rettenmier C. W., Sacca R., Roussel M. F., Look A. T., Stanley E. R. The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell. 1985 Jul;41(3):665–676. doi: 10.1016/s0092-8674(85)80047-7. [DOI] [PubMed] [Google Scholar]
  68. Stach R. W., Shooter E. M. The biological activity of cross-linked beta nerve growth factor protein. J Biol Chem. 1974 Oct 25;249(20):6668–6674. [PubMed] [Google Scholar]
  69. Stöckel K., Paravicini U., Thoenen H. Specificity of the retrograde axonal transport of nerve growth factor. Brain Res. 1974 Aug 23;76(3):413–421. doi: 10.1016/0006-8993(74)90818-x. [DOI] [PubMed] [Google Scholar]
  70. Sugiyama K., Suzuki Y., Furuta H. Histamine-release induced by 7S nerve-growth factor of mouse submandibular salivary glands. Arch Oral Biol. 1985;30(1):93–95. doi: 10.1016/0003-9969(85)90031-7. [DOI] [PubMed] [Google Scholar]
  71. Szutowicz A., Frazier W. A., Bradshaw R. A. Subcellular localization of nerve growth factor receptors. Thirteen-day chick embryo brain. J Biol Chem. 1976 Mar 10;251(5):1516–1523. [PubMed] [Google Scholar]
  72. Thoenen H., Angeletti P. U., Levi-Montalcini R., Kettler R. Selective induction by nerve growth factor of tyrosine hydroxylase and dopamine- -hydroxylase in the rat superior cervical ganglia. Proc Natl Acad Sci U S A. 1971 Jul;68(7):1598–1602. doi: 10.1073/pnas.68.7.1598. [DOI] [PMC free article] [PubMed] [Google Scholar]
  73. Thoenen H., Barde Y. A. Physiology of nerve growth factor. Physiol Rev. 1980 Oct;60(4):1284–1335. doi: 10.1152/physrev.1980.60.4.1284. [DOI] [PubMed] [Google Scholar]
  74. Unsicker K., Krisch B., Otten U., Thoenen H. Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids. Proc Natl Acad Sci U S A. 1978 Jul;75(7):3498–3502. doi: 10.1073/pnas.75.7.3498. [DOI] [PMC free article] [PubMed] [Google Scholar]
  75. Varon S., Nomura J., Shooter E. M. The isolation of the mouse nerve growth factor protein in a high molecular weight form. Biochemistry. 1967 Jul;6(7):2202–2209. doi: 10.1021/bi00859a043. [DOI] [PubMed] [Google Scholar]
  76. Varon S., Normura J., Shooter E. M. Reversible dissociation of the mouse nerve growth factor protein into different subunits. Biochemistry. 1968 Apr;7(4):1296–1303. doi: 10.1021/bi00844a008. [DOI] [PubMed] [Google Scholar]
  77. Weinberger C., Hollenberg S. M., Rosenfeld M. G., Evans R. M. Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product. Nature. 1985 Dec 19;318(6047):670–672. doi: 10.1038/318670a0. [DOI] [PubMed] [Google Scholar]
  78. Whittemore S. R., Ebendal T., Lärkfors L., Olson L., Seiger A., Strömberg I., Persson H. Development and regional expression of beta nerve growth factor messenger RNA and protein in the rat central nervous system. Proc Natl Acad Sci U S A. 1986 Feb;83(3):817–821. doi: 10.1073/pnas.83.3.817. [DOI] [PMC free article] [PubMed] [Google Scholar]
  79. Williams L. R., Varon S., Peterson G. M., Wictorin K., Fischer W., Bjorklund A., Gage F. H. Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection. Proc Natl Acad Sci U S A. 1986 Dec;83(23):9231–9235. doi: 10.1073/pnas.83.23.9231. [DOI] [PMC free article] [PubMed] [Google Scholar]

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